AIDS win be our first priority, but in two years' time we don't know where AIDS research will stand, so we are also thinking of activity on other diseases.

Our goal is not to completely eradicate the infection - that would be very difficult - but to produce a vaccine that will prevent not infection but disease. I think this is more possible.

The idea of the live-virus vaccine is to produce in a continuous way some viral antigens.

It's clear that prevention will never be sufficient. That's why we need a vaccine that will be safe.

I've participated in meetings where there were concerns by ethical experts. There is no clear solution.

My proposal now is to test a vaccine first on people who have been infected, and if you show some efficacy at this level, you might be able to go further to study uninfected people in a population with a high rate of infection.

We don't know why, but there are some gradients of infection.