Dedicated researchers seek better treatments and cures for diabetes, kidney disease, Alzheimer's and every form of cancer. But these scientists face an array of disincentives. We can do better.

For those of us who have lost loved ones in their prime - as I did when my father and other relatives succumbed - even one of those years would have been a precious gift.

In the four decades of philanthropy that have paralleled my business career, I've found that the same principles apply whether you're providing access to capital to grow a business, creating a new paradigm for medical research, or pioneering innovative approaches to education: Empower the most talented people in each field and encourage them to pursue their passions.

You've got to treat people as equals, and make them feel like it's their company. I don't know if I've had any impact or helped persuade Frank [to sell Eastern]. But, I can tell you, there were many discussions on the subject.

There's no substitute for rolling up your sleeves and working with the people who can make a difference. They get the benefit of your participation and you gain a direct understanding of the real problems and potential solutions, which makes you a more informed giver.

I decided to shift my energy and concentration into changing my lifestyle and diet and taking charge of my own illness.

The federal investment in finding cures for cancer - $3 billion annually [as of 1999] - is less than ... zero ... point ... zero ... zero ... zero ... four ... percent of our gross domestic product, or about one-seventh of what Americans spend on beauty products.