Books and novels in particular that grapple with quite a few things are difficult to explain, so I think that first line can come in a substitute for trying to form a longer sense of what the book is about.
Alice SeboldThere was our father, the heart we knew held all of us. Held us heavily and desperately, the doors of his heart opening and closing with the rapidity of stops on an instrument, the quiet felt closures, the ghostly fingering, practice and practice and then, incredibly, sound and melody and warmth.
Alice Sebold