The most important thing to remember about depression is this: you do not get the time back. It is not tacked on at the end of your life to make up for the disaster years. Whatever time is eaten by a depression is gone forever. The minutes that are ticking by as you experience the illness are minutes you will not know again.

I'm a huge believer in science. But I don't think it explains everything.

Though many schizophrenics become curiously attached to their delusions, the fading of the nondelusional world puts them in loneliness beyond all reckoning, a fixed residence on a noxious private planet they can never leave, and where they can receive no visitors.

I think morality is more important than ever before. As we gain more power, the question of what we do with it becomes more and more crucial, and we are very close to really having divine powers of creation and destruction. The future of the entire ecological system and the future of the whole of life is really now in our hands. And what to do with it is an ethical question and also a scientific question.

I met people on college campuses who were defining themselves as genderqueer to express revolutionary feelings, or to communicate their individuality; they were gender fluid without being gender dysphoric. This phenomenon may be culturally significant, but it has only a little bit in common with the people who feel they can have no authentic self in their birth gender.

I was in fact anxious about whether I would be any good at being a father. And then I met so many people who had been good parents under difficult circumstances, and I felt inspired by them.

Depression is the flaw in love. To be creatures who love, we must be creatures who can despair at what we lose, and depression is the mechanism of that despair.