There is a line that I always loved from Lucretius. He said, "The sublime is the art of exchanging easier for more difficult pleasures." The presumption of that formulation is that the more difficult pleasures are actually better than the easier pleasures. That is why one makes the exchange.

There is a false moral imperative that seems to be all-around us that treatment of depression, the medications and so on, are an artifice, and that it's not natural. And I think that's very misguided. It would be natural for people's teeth to fall out, but there is nobody militating against toothpaste, at least not in my circles.

The most important thing to remember about depression is this: you do not get the time back. It is not tacked on at the end of your life to make up for the disaster years. Whatever time is eaten by a depression is gone forever. The minutes that are ticking by as you experience the illness are minutes you will not know again.

Depression means that you have no point of view.

Science still won't explain the mysterious nature of love and despair.

If some glorious angel suddenly descended through my living room ceiling and offered to take away the children I have and give me other, better children — more polite, funnier, nicer, smarter — I would cling to the children I have and pray away that atrocious spectacle.

The strengthening of faith, I think, is the ultimate goal of organized religion altogether.