To actually feel like you've done something good with your life and you're useful to others is what I was always wanting, and was always looking for.

Apart from my children, spending time with refugees was the greatest gift... the greatest life lesson I could ever receive.

The cost of testing for BRCA1 and BRCA2, at more than $3,000 in the United States, remains an obstacle for many women.

To be in any way a positive contribution, that's all anybody wants to be. It's all I've ever wanted to be. I wanted to be an artist, be a mother. You want to feel that in your life you've been of use, in whatever way that comes out.

With my family, I'm trying to raise them to have respect for all people and make friends around the world and feel at home with the world and really live a truly global life because I think it's what forms them and it's really important to me.

Children should be allowed to express themselves in whatever way they wish without anybody judging them because it is an important part of their growth... Society always has something to learn when it comes to the way we judge each other, label each other. We have far to go.

Working with [Robert] De Niro taught me a lot about being an actor's director.