Every story has already been told. Once you've read Anna Karenina, Bleak House, The Sound and the Fury, To Kill a Mockingbird and A Wrinkle in Time, you understand that there is really no reason to ever write another novel. Except that each writer brings to the table, if she will let herself, something that no one else in the history of time has ever had.

[President Johnson] had the political will to say that having one in five Americans living in the kind of abject conditions their fellow citizens associated with Third World countries and the novels of Dickens was as dangerous as any battlefield enemy.

... It was the idea of facing a future skimming the surface of life, winging my way in and out of other people's crises, confusions, and passages, engaging them enough to get the story, but never enough to be indelibly touched by what I had seen or heard.

You realize that especially when you're writing a book like this, looking back on your life, that there's just such a depth of understanding you acquire over time with the help of the people who love you that that's when you can really get down to what you really think and believe.

Your kids are launched. You love your work but you understand how to place it in the panorama of the rest of your life. There's this line in the book, and when I wrote it I thought yes, that's it - if you think of life as a job, maybe by the time you get to, say, in my case, 60, you've finally gotten good at it.

knowledge of our own mortality is the greatest gift God ever gives us.

God bless the physician who warms the speculum or holds your hand and looks into your eyes. Perhaps one subtext of the health caredebate is a yen to be treated like a whole person, not just an eye, an ear, a nose or a throat. A yen to be human again, on the part of patient and doctor alike.