People relate to things that feel real to them. All the good, happy, over-sexed and moneyed endings on TV are not the way most of us feel in our lives. The success of 'E.R.,' I think, is not relying on overly sentimental stories that are solved where people's lives wrap up nicely with happy endings.

I just spent a lot of time on 'ER' for that eight years. I also started working when I was 16, so by the time I left 'ER,' I was 40 years old, I had this incredible experience, my wife had this great company, we had four kids, it was like, 'Let's go to New York and live for a while and make that the priority.'

I was spoiled by theater, where there is no editor.

David Fincher is a longtime friend. As a director, my wife had worked with him as a makeup artist when he would do Madonna videos years before, and his child and my oldest child were in preschool together, so we're kind of dad-friends through that, too.

There are definitely roles within this industry that are industry-related, but to be a good actor, you really have to want to act first. At the same time, my goal was never to go to Hollywood to make movies. I think if you come here with that attitude, then you've missed a few steps.

I didn't start jogging or running until I was 37 years old. It was something that really helped me change my life.

So I was hugely thrilled that my first scene ever on camera was with Hal Holbrook.