[M]y work, which I've done for a long time, was not pursued in order to gain the praise I now enjoy, but chiefly from a craving after knowledge, which I notice resides in me more than in most other men. And therewithal, whenever I found out anything remarkable, I have thought it my duty to put down my discovery on paper, so that all ingenious people might be informed thereof.

I have divers times endeavoured to see and to know, what parts the Blood consists of; and at length I have observ'd, taking some Blood out of my own hand, that it consists of small round globuls driven through a Crystalline humidity or water.

I have divers times examined the same matter (human semen) from a healthy man... not from a sick man... nor spoiled by keeping... for a long time and not liquefied after the lapse of some time... but immediately after ejaculation before six beats of the pulse had intervened; and I have seen so great a number of living animalcules... in it, that sometimes more than a thousand were moving about in an amount of material the size of a grain of sand... I saw this vast number of animalcules not all through the semen, but only in the liquid matter adhering to the thicker part.

I've spent more time than many will believe [making microscopic observations], but I've done them with joy, and I've taken no notice those who have said why take so much trouble and what good is it?

Man has always to be busy with his thoughts if anything is to be accomplished.

In the year 1657 I discovered very small living creatures in rain water.

[M]y work, which I've done for a long time, was not pursued in order to gain the praise I now enjoy, but chiefly from a craving after knowledge, which I notice resides in me more than in most other men. And therewithal, whenever I found out anything remarkable, I have thought it my duty to put down my discovery on paper, so that all ingenious people might be informed thereof.