There is nothing more stimulating than a case where everything goes against you.

It may have been a comedy, or it may have been a tragedy. It cost one man his reason, it cost me a blood-letting, and it cost yet another man the penalties of the law. Yet there was certainly an element of comedy. Well, you shall judge for yourselves.

Do you know, Watson," said he, "that it is one of the curses of a mind with a turn like mine that I must look at everything with reference to my own special subject. You look at these scattered houses, and you are impressed by their beauty. I look at them, and the only thought which comes to me is a feeling of their isolation and of the impunity with which crime may be committed there.

My life is spent in one long effort to escape from the commonplaces of existence. These little problems help me to do so.

if i could be assured of your destruction, i would in the interest of the public, cheerfully accept my death.

I must apologize for calling so late," said he, "and I must further beg you to be so unconventional as to allow me to leave your house presently by scrambling over your back garden wall.

For the one and only time I caught a glimpse of a great heart as well as of a great brain.