To underestimate oneself is as much an exaggeration of one's powers than the other.

The fair sex is your department.

Do you know, Watson," said he, "that it is one of the curses of a mind with a turn like mine that I must look at everything with reference to my own special subject. You look at these scattered houses, and you are impressed by their beauty. I look at them, and the only thought which comes to me is a feeling of their isolation and of the impunity with which crime may be committed there.

The stage lost a fine actor, even as science lost an acute reasoner, when [Holmes] became a specialist in crime.

It is not my intention to be fulsome, but I confess that I covet your skull.

It isn't true that the laws of nature have been capriciously disturbed; that snakes have talked; that women have been turned into salt; that rods have brought water out of rocks.

The more featureless and commonplace a crime is, the more difficult it is to bring it home.