How wise and how merciful is that provision of nature by which his earthly anchor is usually loosened by many little imperceptible tugs, until his consciousness has drifted out of its untenable earthly harbor into the great sea beyond!

By a man's finger-nails, by his coat-sleeve, by his boots, by his trouser-knees, by the callosities of his forefinger and thumb, by his expression, by his shirt-cuff — By each of these things a man's calling is plainly revealed. That all united should fail to enlighten the competent inquirer in any case is almost inconceivable. You know that a conjurer gets no credit when once he has explained his trick; and if I show you too much of my method of working, you will come to the conclusion that I am a very ordinary individual after all.

You're not hurt, Watson? For God's sake, say that you are not hurt!" It was worth a wound -- it was worth many wounds -- to know the depth of loyalty and love which lay behind that cold mask. The clear, hard eyes were dimmed for a moment, and the firm lips were shaking. For the one and only time I caught a glimpse of a great heart as well as of a great brain. All my years of humble but single-minded service culminated in that moment of revelation.

When a doctor does go wrong he is the first of criminals. He has nerve and he has knowledge.

If in 100 years I am only known as the man who invented Sherlock Holmes then I will have considered my life a failure.

You yourself may not be luminous, but you are a conductor of light.

Watson. Come at once if convenient. If inconvenient, come all the same.