He is not a bad fellow, though an absolute imbecile in his profession. He has one positive virtue. He is as brave as a bulldog and as tenacious as a lobster if he gets his claws upon anyone.

Love has been taken away from the poets, and has been brought within the domain of true science. It may prove to be one of the great cosmic elementary forces. When the atom of hydrogen draws the atom of chlorine towards it to form the perfected molecule of hydrochloric acid, the force which it exerts may be intrinsically similar to that which draws me to you. Attraction and repulsion appear to be the primary forces. This is attraction.

A fine horse or a beautiful woman, I cannot look at them unmoved, even now when seventy winters have chilled my blood.

It is, of course, a trifle, but there is nothing so important as trifles.

"Recognising, as I do, that you are the second highest expert in Europe" "Indeed, sir! May I inquire who has the honour to be the first?" Asked Holmes, with some asperity. "To the man of precised, scientific mind the work of Monsieur Bertillon must always appeal strongly." "Then had you not better consult him?" "I said, sir, to the precisely scientific mind. But as a practical man of affairs it is acknowledged that you stand alone. I trust, sir, that I have not inadvertently--" "Just a little," said Holmes.

I consider that a man's brain originally is like a little empty attic, and you have to stock it with such furniture as you choose. [...] It is a mistake to think that that little room has elastic walls and can distend to any extent. [...] It is of the highest importance, therefore, not to have useless facts elbowing out the useful ones.

An absence of antecedents and of relatives is sometimes an aid rather than an impediment to social advancement . . .