When the impossible has been eliminated, all that remains no matter how improbable is possible.

There's an east wind coming all the same, such a wind as never blew on England yet. It will be cold and bitter, Watson, and a good many of us may wither before its blast. But it's God's own wind none the less and a cleaner, better stronger land will lie in the sunshine when the storm has cleared.

Everything comes in circles. [...] The old wheel turns, and the same spoke comes up. It's all been done before, and will be again.

It is a capital mistake to theorize before one has data.

I suppose I shall have to compound a felony as usual.

That which is clearly known hath less terror than that which is but hinted at and guessed.

Life, my dear Watson, is infinitely stranger than fiction; stranger than anything which the mind of man could invent. We could not conceive the things that are merely commonplace to existence. If we could hover over this great city, remove the roofs, and peep in at the things going on, it would make all fiction, with its conventionalities and foreseen conclusions flat, stale and unprofitable.