The chief proof of man's real greatness lies in his perception of his own smallness.

The setting is a worthy one, if the devil did desire to have a hand in the affairs of men.

His ignorance was as remarkable as his knowledge. Of contemporary literature, philosophy and politics he appeared to know next to nothing... My surprise reached a climax, however, when I found incidentally that he was ignorant of the Copernican Theory and of the composition of the Solar System.

Crime is common. Logic is rare. Therefore it is upon the logic rather than upon the crime that you should dwell.

Sherlock Holmes took his bottle from the corner of the mantel-piece, and his hypodermic syringe from its neat morocco case. With his long, white, nervous fingers he adjusted the delicate needle, and rolled back his left shirt-cuff. For some little time his eyes rested thoughtfully upon the sinewy forearm and wrist, all dotted and scarred with innumerable puncture-marks. Finally, he thrust the sharp point home, pressed down the tiny piston, and sank back into the velvet-lined armchair with a long sigh of satisfaction.

[Sherlock Holmes:] The temptation to form premature theories upon insufficient data is the bane of our profession.

He spoke wistfully of a sudden leaving, a breaking of old ties, a flight into a strange world, ending in this dreary valley, and Ettie listened, her dark eyes gleaming with pity and with sympathy - those two qualities which may turn so rapidly and so naturally to love.