The chief proof of man's real greatness lies in his perception of his own smallness.

I had neither kith nor kin in England, and was therefore as free as air -- or as free as an income of eleven shillings and sixpence a day will permit a man to be. Under such circumstances, I naturally gravitated to London, that great cesspool into which all the loungers and idlers of the Empire are irresistibly drained.

Do you know, Watson," said he, "that it is one of the curses of a mind with a turn like mine that I must look at everything with reference to my own special subject. You look at these scattered houses, and you are impressed by their beauty. I look at them, and the only thought which comes to me is a feeling of their isolation and of the impunity with which crime may be committed there.

Heaven, too, was very near to them in those days. God's direct agency was to be seen in the thunder and the rainbow, the whirlwind and the lightning. To the believer, clouds of angels and confessors, and martyrs, armies of the sainted and the saved, were ever stooping over their struggling brethren upon earth, raising, encouraging, and supporting them.

He [Professor Moriarty] is the Napoleon of crime, Watson. He is the organizer of half that is evil and of nearly all that is undetected in this great city. He is a genius, a philosopher, an abstract thinker. He has a brain of the first order.

What you do in this world is a matter of no consequence. The question is, what can you make people believe that you have done?

How sweet the morning air is! See how that one little cloud floats like a pink feather from some gigantic flamingo. Now the red rim of the sun pushes itself over the London cloud-bank. It shines on a good many folk, but on none, I dare bet, who are on a stranger errand than you and I. How small we feel with our petty ambitions and strivings in the presence of the great elemental forces of Nature!