No man burdens his mind with small matters unless he has some very good reason for doing so.

Now is the dramatic moment of fate, Watson, when you hear a step upon the stair which is walking into your life, and you know not whether for good or ill.

Oh how I've missed you, Holmes.

Let us hear the suspicions. I will look after the proofs.

If I had never touched Holmes, who has tended to obscure my higher work, my position in literature would at the present moment be a more commanding one.

The husband was a teetotaller, there was no other woman, and the conduct complained of was that he had drifted into the habit of winding up every meal by taking out his false teeth and hurling them at his wife.

The less experienced a doctor is, the higher are his notions of professional dignity . . .