The world is big enough for us. No ghosts need apply.

I have heard, Mr. Holmes, that you can see deeply into the manifold wickedness of the human heart.

if i could be assured of your destruction, i would in the interest of the public, cheerfully accept my death.

Circumstantial evidence is a very tricky thing. It may seem to point very straight to one thing, but if you shift your own point of view a little, you may find it pointing in an equally uncompromising manner to something entirely different

I have mastered the principles of several religions. They have all shocked me by the violence which I should have to do to my reason to accept the dogmas of any one of them.

I think you want a little unofficial help. Three undetected murders in one year won't do, Lestrade. But you handled the Molesey Mystery with less than your usual - that's to say, you handled it fairly well.

A client is to me a mere unit, a factor in a problem.