There are no fools so troublesome as those who have some wit.

"Recognising, as I do, that you are the second highest expert in Europe" "Indeed, sir! May I inquire who has the honour to be the first?" Asked Holmes, with some asperity. "To the man of precised, scientific mind the work of Monsieur Bertillon must always appeal strongly." "Then had you not better consult him?" "I said, sir, to the precisely scientific mind. But as a practical man of affairs it is acknowledged that you stand alone. I trust, sir, that I have not inadvertently--" "Just a little," said Holmes.

My life is spent in one long effort to escape from the commonplaces of existence. These little problems help me to do so.

You will remember that I remarked the other day, just before we went into the very simple problem presented by Miss Mary Sutherland, that for strange effects and extraordinary combinations we must go to life itself, which is always far more daring than any effort of the imagination.” “A proposition which I took the liberty of doubting.” “You did, Doctor, but none the less you must come round to my view, for otherwise I shall keep on piling fact upon fact on you until your reason breaks down under them and acknowledges me to be right.

Everything comes in circles. [...] The old wheel turns, and the same spoke comes up. It's all been done before, and will be again.

Three quiet days. This hell fiend is like a cat with a mouse. She lets me loose only to pounce upon me again. I am never so frightened as when every thing is still.

I had neither kith nor kin in England, and was therefore as free as air -- or as free as an income of eleven shillings and sixpence a day will permit a man to be. Under such circumstances, I naturally gravitated to London, that great cesspool into which all the loungers and idlers of the Empire are irresistibly drained.