Living, as I do, in an educated and scientific atmosphere, I could not have conceived that the first principles of zoology were so little known. Is it possible that you do not know the elementary fact in comparative anatomy, that the wing of a bird is really the forearm, while the wing of a bat consists of three elongated fingers with membranes between?

Just see how it glints and sparkles. Of course it is a nucleus and focus of crime. Every good stone is. They are the devil

Once or twice in my career I feel that I have done more real harm by my discovery of the criminal than ever he had done by his crime. I have learned caution now, and I had rather play tricks with the law of England than with my own conscience.

'There's no need for fiction in medicine,' remarks Foster... 'for the facts will always beat anything you fancy.'

If in 100 years I am only known as the man who invented Sherlock Holmes then I will have considered my life a failure.

Philosophy, astronomy, and politics were marked at zero, I remember. Botany variable, geology profound as regards the mud stains from any region within fifty miles of town, chemistry eccentric, anatomy unsystematic, sensational literature and crime records unique, violin player, boxer, swordsman, lawyer, and self-poisoner by cocaine and tobacco.

On glancing over my notes of the seventy odd cases in which I have during the last eight years studied the methods of my friend Sherlock Holmes, I find many tragic, some comic, a large number merely strange, but none commonplace; for, working as he did rather for the love of his art than for the acquirement of wealth, he refused to associate himself with any investigation which did not tend towards the unusual, and even the fantastic.