What can we know? What are we all? Poor silly half-brained things peering out at the infinite, with the aspirations of angels and the instinct of beasts.

If you want to write good copy, you must be where the things are.

The emotional qualities are antagonistic to clear reasoning.

So swift, silent and furtive were his movements like those of a trained bloodhound picking out a scent, that I could not but think what a terrible criminal he would have made had he turned his energy and sagacity against the law instead of exerting them in its defense. -Dr. Watson, The Sign of the Four

Well, well, my dear fellow, be it so. We have shared this same room for some years, and it would be amusing if we ended by sharing the same cell. (...)

A study of family portraits is enough to convert a man to the theory of reincarnation.

There's an east wind coming all the same, such a wind as never blew on England yet. It will be cold and bitter, Watson, and a good many of us may wither before its blast. But it's God's own wind none the less and a cleaner, better stronger land will lie in the sunshine when the storm has cleared.