I fear that if the matter is beyond humanity, it is certainly beyond me.

What the deuce is it to me?" he interrupted impatiently: "you say that we go round the sun. If we went round the moon it would not make a pennyworth of difference to me or to my work.

By the way, Doctor, I shall want your cooperation.' 'I shall be delighted.' 'You don't mind breaking the law?' 'Not in the least.' 'Nor running a chance of arrest?' 'Not in a good cause.' 'Oh, the cause is excellent!' 'Then I am your man.' 'I was sure that I might rely on you.

It is, of course, a trifle, but there is nothing so important as trifles.

He [Professor Moriarty] is the Napoleon of crime, Watson. He is the organizer of half that is evil and of nearly all that is undetected in this great city. He is a genius, a philosopher, an abstract thinker. He has a brain of the first order.

Indeed, I cannot think why the whole bed of the ocean is not one solid mass of oysters, so prolific the creatures seem. Ah, I am wandering! Strange how the brain controls the brain! What was I saying, Watson?

Desultory readers are seldom remarkable for the exactness of their learning.