Philosophy, astronomy, and politics were marked at zero, I remember. Botany variable, geology profound as regards the mud stains from any region within fifty miles of town, chemistry eccentric, anatomy unsystematic, sensational literature and crime records unique, violin player, boxer, swordsman, lawyer, and self-poisoner by cocaine and tobacco.

As a rule, said Holmes, the more bizarre a thing is the less mysterious it proves to be. It is your commonplace, featureless crimes which are really puzzling, just as a commonplace face is the most difficult to identify.

Do you know, Watson," said he, "that it is one of the curses of a mind with a turn like mine that I must look at everything with reference to my own special subject. You look at these scattered houses, and you are impressed by their beauty. I look at them, and the only thought which comes to me is a feeling of their isolation and of the impunity with which crime may be committed there.

It seems to leave the darkness rather blacker than before.

Why should people ever take credit for charity when they must know that they cannot gain as much pleasure out of their guineas in any other fashion?

'There's no need for fiction in medicine,' remarks Foster... 'for the facts will always beat anything you fancy.'

Life, my dear Watson, is infinitely stranger than fiction; stranger than anything which the mind of man could invent. We could not conceive the things that are merely commonplace to existence. If we could hover over this great city, remove the roofs, and peep in at the things going on, it would make all fiction, with its conventionalities and foreseen conclusions flat, stale and unprofitable.