He [Professor Moriarty] is the Napoleon of crime, Watson. He is the organizer of half that is evil and of nearly all that is undetected in this great city. He is a genius, a philosopher, an abstract thinker. He has a brain of the first order.

A client is to me a mere unit, a factor in a problem.

'There's no need for fiction in medicine,' remarks Foster... 'for the facts will always beat anything you fancy.'

Do you remember what Darwin says about music? He claims that the power of producing and appreciating it existed among the human race long before the power of speech was arrived at. Perhaps that is why we are so subtly influenced by it. There are vague memories in our souls of those misty centuries when the world was in its childhood.' That's a rather broad idea,' I remarked. One's ideas must be as broad as Nature if they are to interpret Nature,' he answered.

It has long been an axiom of mine that the little things are infinitely the most important.

One dumb-bell, Watson! Consider an athlete with one dumb-bell. Picture to yourself the unilateral development - the imminent danger of a spinal curvature. Shocking, Watson, shocking!

I suppose I shall have to compound a felony as usual.