Life is infinitely stranger than anything which the mind of man could invent.

The ways of fate are indeed hard to understand. If there is not some compensation hereafter, then the world is a cruel jest.

Living, as I do, in an educated and scientific atmosphere, I could not have conceived that the first principles of zoology were so little known. Is it possible that you do not know the elementary fact in comparative anatomy, that the wing of a bird is really the forearm, while the wing of a bat consists of three elongated fingers with membranes between?

What the deuce is it to me?" he interrupted impatiently: "you say that we go round the sun. If we went round the moon it would not make a pennyworth of difference to me or to my work.

What is the meaning of it, Watson? said Holmes solemnly as he laid down the paper. "What object is served by this circle of misery and violence and fear? It must tend to some end, or else our universe is ruled by chance, which is unthinkable. But what end? There is the great standing perennial problem to which human reason is as far from an answer as ever.

A study in scarlet, eh? Why shouldn't we use a little art jargon? There's the scarlet thread of murder running through the colourless skein of life, and our duty is to unravel it, and isolate it, and expose every inch of it.

You have a grand gift for silence, Watson. It makes you quite invaluable as a companion.