Anyone who has tried to build something that changes people's lives sometimes finds life to be a distraction, and finds people who don't care as much as they do to be annoying.

I wanted to be a genetic engineer. That was my goal in college. I wanted to figure out what the codon sequence was that causes replication in a cardio myopathic virus. That was my goal.

The thing that enchants me the most is the ability women have to feel other people's pain. The total empathy that women have is extraordinary.

I think you're sort of always waiting, wondering when the word "cut" is going to be said when you're doing a scene. Like you're there and you're doing the scene and you're always sort of like, ‘Okay. Are they going to call cut? How far are we taking this? Are they going to call cut?’

I think guys wind up after a while not wanting another guy sleeping with the girl they're with. But eventually everyone wants something more. We all have that desire for something special, something committed. We all want to be The One.

I feel like a fraud... My name is not even actually Ashton. Ashton is my middle name.

After 'Punk'd,' my company Katalyst did a deal with AOL to produce short-form content for the Web. At that time it was a different game. If you got front-page coverage on any popular website, you could probably get a push.