In mathematics we find the primitive source of rationality; and to mathematics must the biologists resort for means to carry out their researches.
Auguste ComteEvery attempt to employ mathematical methods in the study of chemical questions must be considered profoundly irrational and contrary to the spirit of chemistry.... if mathematical analysis should ever hold a prominent place in chemistry -- an aberration which is happily almost impossible -- it would occasion a rapid and widespread degeneration of that science.
Auguste Comte