Lots of medications work for a month, or a year, and then stop working.

Most writers spend their lives standing a little apart from the crowd, watching and listening and hoping to catch that tiny hint of despair, that sliver of malice, that makes them think, 'Aha, here is the story.'

I love the novel of 'The English Patient'; I think it's a profoundly beautiful novel. I love the movie of 'The English Patient'; I think it's a profoundly beautiful movie. And they're totally different. You accept each on its own terms, and that's kind of the ideal.

I'd never written nonfiction about the war on drugs, but I know a tremendous amount about it: I taught a class on it for seven years. I was putting into words the stuff I was teaching, and I was writing it up and thought, "Dude, you're writing a book."

Gym class was, of course, where the strongest, best-looking kids were made captains and chose us spazzes last. More important, it was where the figures of supposed authority allowed them to do so. Forget the work our parents did molding our minds and values. Everything fell apart as soon as we put on those maroon polyester gym suits.

Whatever my intentions, whatever the truth of my claim, I had no business giving a lecture to a total stranger.

I certainly don't think it's inevitable that we don't love children who don't carry our own DNA. If that were true we wouldn't have millions of successful adoptions to consider. I do think that it's harder to love a child when you come into that child's life after the unrequited passion of infancy and early childhood has passed.