To preserve one's mind intact through a modern college education is a test of courage and endurance, but the battle is worth it and the stakes are the highest possible to man: the survival of reason.

We are on strike against martyrdom—and against the moral code that demands it. We are on strike against those who believe that one man must exist for the sake of another. We are on strike against the morality of cannibals, be it practiced in body or in spirit. We will not deal with men on any terms but ours—and our terms are a moral code which holds that man is an end in himself and not the means to any end of others.

I am older than you. Believe me, there is no other way to live on earth. Men are not open to truth or reason. They cannot be reached by a rational argument. The mind is powerless against them. Yet we have to deal with them. If we want to accomplish anything, we have to deceive them into letting us accomplish it. Or force them. They understand nothing else. We cannot expect their support for any endeavor of the intellect, for any goal of the spirit. They are nothing but vicious animals. They are greedy, self-indulgent, predatory dollar-chasers

Self-esteem is reliance on one's power to think. It cannot be replaced by one's power to deceive. The self-confidence of a scientist and the self-confidence of a con man are not interchangeable states, and do not come from the same psychological universe. The success of a man who deals with reality augments his self-confidence. The success of a con man augments his panic.

My greatest personal mistake is ever to allow a word or moment that “doesn’t count,” i.e., that I do not refer to my own basic principles. Every word, every action, every moment counts. (This is the pattern on which everybody makes mistakes [or] becomes irrational — not relating their one action or one conviction to another.

Achievement of your happiness is the only moral purpose of your life, and that happiness, not pain or mindless self-indulgence, is the proof of your moral integrity, since it is the proof and the result of your loyalty to the achievement of your values.

There's nothing of any importance in life — except how well you do your work. Nothing. Only that. Whatever else you are, will come from that. It's the only measure of human value.