You have to take ownership and leadership of tomorrow. For that to be possible, you have to strengthen your capacity and widen your vision as a global citizen.

Three decades into this crisis, let us set our sights on achieving the "three zeros" zero new HIV infections, zero discrimination and zero AIDS-related deaths.

World military spending has now risen to over $1.2 trillion. This incredible sum represents 2.5 per cent of GDP (global gross domestic product). Even if 1 per cent of it were redirected towards development, the world would be much closer to achieving the Millennium Development Goals.

I have been urging the leaders to listen to the aspirations and challenges of their own people, and engage in dialogue and take very bold measures. Normally, to their regret, these measures and bold reforms come too late, too little.

We hold the future in our hands, together, we must ensure that our grandchildren will not have to ask why we failed to do the right thing, and let them suffer the consequences.

Nuclear terrorism is one of the most serious threats of our time. Even one such attack could inflict mass casualties and create immense suffering and unwanted change in the world forever. This prospect should compel all of us to act to prevent such a catastrophe.

It is only natural that people's wishes and aspirations should be realized by the leaders of the region. As this wind of change blows, it is up to the leaders to seize this opportunity to look for the better future for their own people through bold reforms before it is too late, before the people are forced to take action.