If we want to make the best products, we also have to invest in the best ideas... Every dollar we invested to map the human genome returned $140 to our economy... Today, our scientists are mapping the human brain to unlock the answers to Alzheimer's... Now is not the time to gut these job-creating investments in science and innovation. Now is the time to reach a level of research and development not seen since the height of the Space Race.

We built this country by making things, by producing goods we could sell.

It is absolutely important that we have a unified alliance and that we explain to the Russians that you cannot be a 21st-century superpower, or power, and act like a 20th-century dictatorship.

There are times where I'd say the Oval Office, you use to gather the facts. The decisions you probably make late at night, or at least I do. But there are some times where you think you've made a decision, but during that walk, where you're announcing the decision, you've just got to make sure that, you're prepared to live with it, because as you know George, a lot of these decisions are not - the outcomes are uncertain.

I remember having meetings with Republican senators who initially had been trying to engage [Obamacare] but saw that the politics of 'no' were growing inside the Republican Party.

Number one, it is absolutely critical that we tone down the rhetoric when it comes to the immigration debate, because there has been an undertone that has been ugly. Oftentimes, it has been directed at the Hispanic community. We have seen hate crimes skyrocket in the wake of the immigration debate as it has been conducted in Washington, and that is unacceptable.

Some banks won’t make it. Other banks are going to make sure that we strengthen. All deposits are going to be safe for ordinary people, but we’re going to have to bring out some of these bad assets.