We've got to be able to have a conversation and recognize we're all Americans; we all want the best for this country. We may have some disagreements in terms of how to get there, but all of us want to make sure that our economy is strong, that jobs are growing. All of us want to make sure that people aren't bankrupt when they get sick. All of us want to make sure that young people can afford an education.

When I read history, I [see] what typically happens to presidents and the other party during tumultuous times and how people react when the economy is collapsing and they're losing their homes, losing their pensions - it sort of tracks, what ended up happening, because some of that is human nature.

Persevere. Nothing worthwhile is easy.

In the campaign back in 2007, 2008, people would say, "Oh, he's being naïve. He thinks that there's no red states and blue states. And wait 'til he gets here." And I will confess that, I didn't fully appreciate the ways in which individual senators or members of Congress now are pushed to the extremes by their voter bases. I did not expect, particularly in the midst of crisis, just how severe that partisanship would be.

Cool, logical, big-eared and level-headed, the center of Star Trek's optimistic, inclusive vision of humanity's future. I loved Spock.

Cuba is actually one where I am more optimistic because of the unique nature of Cuba - 90 miles off our shore with a massive ex-patriot population, now Cuban-American population that still have deep links to the island. There I am more confident that over time that the winds of commerce and telecommunication and travel start shifting the nature of that regime. But that's a small country which has almost a unique relationship to us.

Iran has to live up to its international obligations. . . . The president has said that our patience is not unlimited.