America at its best is inclusive and not exclusive.

If we want to make the best products, we also have to invest in the best ideas... Every dollar we invested to map the human genome returned $140 to our economy... Today, our scientists are mapping the human brain to unlock the answers to Alzheimer's... Now is not the time to gut these job-creating investments in science and innovation. Now is the time to reach a level of research and development not seen since the height of the Space Race.

I've come to embrace the notion that I haven't done enough in my life. I've come to confirm that one's title, even a title like president of the United States, says very little about how well one's life has been led. No matter how much you've done or how successful you've been, there's always more to do, always more to learn, and always more to achieve.

I think the American people can change Washington. But I think that it is not going to change, because somebody from on high directs that change.

In order for us to compete with China, we've also got to make sure, though, that we're taking - taking care of business here at home. If we don't have the best education system in the world, if we don't continue to put money into research and technology that will allow us to create great businesses here in the United States, that's how we lose the competition.

At a certain point you can't help but lose some feel for what's on the ground because you're not on the ground.

Yesterday, John McCain actually said that if he's president that he'll take on, and I quote, 'the old boys network in Washington.' Now I'm not making this up. This is somebody who's been in Congress for twenty-six years, who put seven of the most powerful Washington lobbyists in charge of his campaign. And now he tells us that he's the one who's gonna' to take on the old boys network. The old boys network? In the McCain campaign that's called a staff meeting. Come, on!