With all due respect for the wondrous ways people have invented to amuse themselves and one another on paved surfaces, I find that this exodus from the land makes me unspeakably sad. I think of the children who will never know, intuitively, that a flower is a plant's way of making love, or what silence sounds like, or that trees breathe out what we breathe in.

There is no point treating a depressed person as though she were just feeling sad, saying, 'There now, hang on, you'll get over it.' Sadness is more or less like a head cold- with patience, it passes. Depression is like cancer.

For Lou Ann, life itself was a life-threatening enterprise.

Everything you're sure is right can be wrong in another place.

The arrogance of the able-bodied is staggering. Yes, maybe we'd like to be able to get places quickly, and carry things in both hands but only because we have to keep up with the rest of you ... We would rather be just like us, and have that be all right.

Southern Appalachians have been ridiculed since the country began. In fiction, they're usually depicted in a cartoonish manner. The region is poor, and very suspicious of outsiders, so there's a sort of 'us versus them' situation. They're easy to poke fun at.

A careless way of sauntering across the earth and breaking open its treasures, a terrible dependency on sucking out the world's best juices for ourselves-these may also be our enemies. The changes we dread most may contain our salvation.