What reaches an audience is honesty. If you're saying something truthful that's supposed to be a funny line, it's going to be funny. And if it's supposed to be a serious line, it's going to be serious. But, I don't think there's a distinction between how you play drama or comedy, if it's based in the truth.
Barbra StreisandI'd started going to acting classes at 14, played 'Medea' at 15 and really wanted to be a classical actress.
Barbra Streisand