The moral immune system of this country has been weakened and attacked, and the AIDS virus is the perfect metaphor for it. The malignant neglect of the last twelve years has led to breakdown of our country's immune system, environmentally, culturally, politically, spiritually and physically.

What reaches an audience is honesty. If you're saying something truthful that's supposed to be a funny line, it's going to be funny. And if it's supposed to be a serious line, it's going to be serious. But, I don't think there's a distinction between how you play drama or comedy, if it's based in the truth.

Our role as artist is more controversial now because there are those, claiming the absolute authority of religion, who detest much of our work as much as they detest most of our politics. Instead of rationally debating subjects like abortion or gay rights, they condemn as immoral those who favor choice and tolerance. They disown their own dark side and magnify everyone else's until, at the extreme, doctors are murdered in the name of protecting life. I wonder, who is this God they invoke, who is so petty and mean? Is God really against gun control and food stamps for poor children?

progress, whatever your definition of it, is not inevitable.

If a man wants to get it right, he's looked up to and respected. If a woman wants to get it right, she's difficult or impossible. If he acts, produces and directs, he's called multitalented. If she does the same thing, she's called vain and egotistical.

Everybody's frightened a bit. But how many of us just go through the fear and do it anyway?

I was a personality before I became a person - I am simple, complex, generous, selfish, unattractive, beautiful, lazy and driven.