The incessant driving of the pen over paper causes intense fatigue of the hand and the whole arm because of the continuous ... strain on the muscles and tendons.

All sedentary workers ... suffer from the itch, are a bad colour, and in poor condition ... for when the body is not kept moving the blood becomes tainted, its waste matter lodges in the skin, and the condition of the whole body deteriorates.

Those who work standing ... carpenters, sawyers, carvers, blacksmiths, masons ... are liable to varicose veins ... [because] the strain on the muscles is such that the circulation of the blood is retarded. Standing even for a short time proves exhausting compared with walking and running though it be for a long time ... Nature delights and is restored by alternating and varied actions.

I have noticed bakers with swelled hands, and painful, too; in fact the hands of all such workers become much thickened by the constant pressure of kneading the dough.

[I have seen] workers in whom certain morbid affections gradually arise from some particular posture of the limbs or unnatural movements of the body called for while they work. Such are the workers who all day stand or sit, stoop or are bent double, who run or ride or exercise their bodies in all sorts of [excess] ways. ... the harvest of diseases reaped by certain workers ... [from] irregular motions in unnatural postures of the body.

An acquaintance of mine, a notary by profession, who, by perpetual writing, began first to complain of an excessive wariness of his whole right arm which could be removed by no medicines, and which was at last succeeded by a perfect palsy of the whole arm. . . . He learned to write with his left hand, which was soon thereafter seized with the same disorder.

The mortality of those who dig minerals is very great, and women who marry men of this sort marry again and again. According to Agricola, at the mines in the Carpathian mountains, women have been known to marry seven times.