Of all the things I am not very good at, living in the real world is perhaps the most outstanding.

If you go out on the Appalachian Trail, you have to bring so much more equipment - a tent, sleeping bag - but if you go hiking in England, or Europe, generally, towns and villages are near enough together at the end of the day you can always go to a nice little inn and have a hot bath and something to drink.

As James Surowiecki noted in a New Yorker article, given a choice between developing antibiotics that people will take every day for two weeks and antidepressants that people will take every day for ever, drug companies not surprisingly opt for the latter. Although a few antibiotics have been toughened up a bit, the pharmaceutical industry hasn't given us an entirely new antibiotic since the 1970s.

Science has been quite embattled. It's the most important thing there is. An arts graduate is not going to fix global warming. They may do other valuable things, but they are not going to fix the planet or cure cancer or get rid of malaria.

18th century scientists, the French in particular, seldom did things simply if an absurdly demanding alternative was available.

There is no such thing, incidentally, as one kudo.

In France, a chemist named Pilatre de Rozier tested the flammability of hydrogen by gulping a mouthful and blowing across an open flame, proving at a stroke that hydrogen is indeed explosively combustible and that eyebrows are not necessarily a permanent feature of one's face.