The trouble with energy farming is that the energy isn't always where you want to use it, and it isn't always when you want to use it.

Even for the diseases we don't focus on, cancer, heart disease, you're going to be way better off being sick 10 years from now than any time in the past.

I could name about a dozen paths, and you'd like to have a whole bunch of research on all those paths, and then, eventually, at least four to five companies with really significant financing try and get to big scale, going down and really trying to prove it out.

The first rule of any technology used in a business is that automation applied to an efficient operation will magnify the efficiency. The second is that automation applied to an inefficient operation will magnify the inefficiency.

If you think of global public goods like polio eradication, the kind of risk-taking new approach, philanthropy really does have a role to play there, because government doesn't do R&D about new things naturally as much as it probably should, and so philanthropy's there.

Of my mental cycles, I devote maybe 10 percent to business thinking. Business isn't that complicated. I wouldn't want to put it on my business card.

When I was in college, for the games of that era, I was as hard core as anyone was. I wouldn't say I outgrew it, but you always have to have a finite number of addictions.