Software is a great combination between artistry and engineering. When you finally get done and get to appreciate what you have done it is like a part of yourself that you've put together. I think a lot of the people here feel that way.

Going out in the field, it's always enlightening to see what's working and what's not and to sit down and talk - I was with young girls in south Africa - understanding why our tools for prevention aren't being adopted, and what way may need to invent to help protect them.

If I'd had some set idea of a finish line, don't you think I would have crossed it years ago?

Nobody has a guaranteed position in computer technologies business. We've done some good work, but all of these products become obsolete so fast and the structure of the business as it broadens out is going to be so different.

Microsoft has some assets like Office that have stayed strong and there's so much room for innovation in those.

My fascination is broadly with biology and the fact that our increased understanding of biology allows for breakthroughs in a broad set of diseases.

It is hard to smash a computer when you're laughing.