Measuring programming progress by lines of code is like measuring aircraft building progress by weight.

Eventually we'll be able to sequence the human genome and replicate how nature did intelligence in a carbon-based system.

AIDS itself is subject to incredible stigma.

Software substitution, whether it's for drivers or waiters or nurses ... it's progressing. ... Technology over time will reduce demand for jobs, particularly at the lower end of skill set. ... 20 years from now, labor demand for lots of skill sets will be substantially lower. I don’t think people have that in their mental model.

Being maniacal about something is very helpful.

Hey, size works against excellence.

Certainly, the Windows share of servers is strong.