I have a particular relationship with Vinod Khosla because he's got a lot of very interesting science-based energy startups.

My fascination is broadly with biology and the fact that our increased understanding of biology allows for breakthroughs in a broad set of diseases.

We believe the world changes when the boldest thinking is directed at the toughest problems

Does the e-mail say it's about 'enlargement' - that might be spam.

Looking at these issues as a businessman, I believe that investing in the world's poorest people is the smartest way that our government spends money.

Microsoft is a company that manages imagination.

The spread of online information isn't just good for charities. It's also good for donors. You can go to a site like Charity Navigator, which evaluates nonprofits on their financial health as well as the amount of information they share about their work.