My dream is that every child has enough food to eat, good medical care, and the chance to go to school and even attend college.

Our work in global health is about things like cutting childhood deaths, and every year we continue to make progress there.

(Talking about his first computer) Like all kids we not only fooled around with our toys, we changed them. If you've ever watched a child with a cardboard carton and a box of crayons create a spaceship with cool control panels, or listened to their improvised rules, such as "Red cars can jump all others," then you know that this impulse to make a toy do more is at the heart of innovative childhood play. It is also the essence of creativity.

I have to admit that business-type thoughts do sneak into my head: I hope our customers pay us, I hope this stuff is decent, I hope we get it done on time. The little additions and subtractions that one has to do. Take sales, take costs and try to get that big positive number at the bottom.

A lot of the things that will really improve the world fortunately aren't dependent on Washington doing something different.

If we [Microsoft Corporation] weren't still hiring great people and pushing ahead at full speed, it would be easy to fall behind and become a mediocre company. Fear should guide you, but it should be latent. I have some latent fear. I consider failure on a regular basis.

I'm an investor in a number of biotech companies, partly because of my incredible enthusiasm for the great innovations they will bring.