Legacy is a stupid thing! I don't want a legacy.

People who say they don't see the acceleration of innovation is a wilful blindness. We are innovation at a wonderful speed for the basic things we think everyone should get.

Good programmers stay open minded to that even though there is no obvious way to improve what they've done they... they keep looking and they listen to what other people have to say.

A breakthrough in machine learning would be worth ten Microsofts.

I have $100 billion... You realize I could spend $3 million a day, every day, for the next 100 years? And that's if I don't make another dime.

The worst pandemic in modern history was the Spanish flu of 1918, which killed tens of millions of people. Today, with how interconnected the world is, it would spread faster.

Melinda [Gates] has been my partner in raising the kids and I went from before I met her, intentionally having an unbalanced life, to having a more balanced life with all sorts of fun things that she and I do together.