We are not even close to finishing the basic dream of what the PC can be.

DNA is like a computer program but far, far more advanced than any software ever created.

In poor countries, we still need better ways to measure the effectiveness of the many government workers providing health services. They are the crucial link bringing tools such as vaccines and education to the people who need them most. How well trained are they? Are they showing up to work?

The nuclear industry has this amazing record, even equipment from generations one and two. But nuclear mishaps tend to come in these big events - Chernobyl, Three Mile Island, and now Fukushima - so it's more visible.

I didn't used to wear a watch. Now I have a SPOT watch, which I wear all the time.

Philanthropy should be taking much bigger risks that business. If these are easy problems, business and government can come in and solve them.

When the PC was launched, people knew it was important.