Microsoft does not dominate the software industry by any stretch of the imagination. We have lots of very able competitors who keep us constantly vigilant, and sometimes they beat us to the punch. Microsoft's success to date is based solely on the fact that people like Microsoft software.

You have to be willing to see that sometimes the governments of these poor countries don't come through. You have to think about that as a constraint. How do you help them be better? How do you come up with things that actually work, even in those tough situations.

I admire leaders in science, people who really figure things out like Richard Fineman or people who work on vaccines, tons of people working on [the] HIV vaccine. There's leaders in business, people like Warren Buffett, who've got a certain approach they take that are pretty amazing. There [are] product innovators like Steve Jobs was, where he gets behind a concept and does a fantastic job.

SPAM is taking e-mail, which is a wonderful tool, and exploiting the idea that it's very inexpensive to send mail.

The media covers what’s new – and millions of people dying is nothing new. So it stays in the background, where it’s easier to ignore. But even when we do see it or read about it, it’s difficult to keep our eyes on the problem. It’s hard to look at suffering if the situation is so complex that we don’t know how to help. And so we look away.

Globalization has made copper and other minerals more valuable, and Ghana and Kenya have recently discovered mineral resources.

I never took a day off in my twenties. Not one. And I'm still fanatical, but now I'm a little less fanatical.