Eventually we'll be able to sequence the human genome and replicate how nature did intelligence in a carbon-based system.

In three years, every product my company makes will be obsolete. The only question is whether we will make them obsolete or somebody else will.

In the philanthropy game, you're going for different outcomes: saving childhood lives, having kids grow up - because they don't have malnutrition or disease - that they achieve their full potential. We take for Warren [Buffett] things that, because he's very intelligent about the world but doesn't get to go out in Africa and see what we see, we've taken and say to him where we stand and it's basically a very positive report that his gift has made a phenomenal difference.

But the improvements will happen faster and last longer if we can channel market forces, including innovation that's tailored to the needs of the poorest, to complement what governments and nonprofits do. We need a system that draws in innovators and businesses in a far better way than we do today.

Contrary to Piketty’s rentier hypothesis, I don’t see anyone on the [Forbes 400 list of the wealthiest Americans] whose ancestors bought a great parcel of land in 1780 and have been accumulating family wealth by collecting rents ever since. In America, that old money is long gone - through instability, inflation, taxes, philanthropy, and spending.

I believe in innovation and that the way you get innovation is you fund research and you learn the basic facts.

Life is a lot more fun if you treat its challenges in creative ways.