With the states release today of a set of clear and consistent academic standards, our nation is one step closer to supporting effective teaching in every classroom, charting a path to college and careers for all students, and developing the tools to help all children stay motivated and engaged in their own education. The more states that adopt these college and career based standards, the closer we will be to sharing innovation across state borders and becoming more competitive as a country.

Information technology and business are becoming inextricably interwoven. I don't think anybody can talk meaningfully about one without the talking about the other.

Melinda [Gates] has been my partner in raising the kids and I went from before I met her, intentionally having an unbalanced life, to having a more balanced life with all sorts of fun things that she and I do together.

We're still missing about a dozen vaccines that will make a huge difference. For adults, we've got HIV and TB are still huge; for kids malaria is still killing a half million kids a year out of that 6 million. We probably need some vaccines, but we need a little more data to make sure we're getting the vaccines that will save the most lives.

If you want to build a great company, get the hell out of Silicon Valley.

The world is very disparate, in terms of the US using the most energy per person, and then the other rich countries - Europe, Japan, New Zealand - using about half of what we do, and then the world average being about a fifth of what we use, with China just now surpassing the world average.

When you have the medical advances you think will they be available to everyone. Will they not just be for the rich world or even just the rich people and the rich world? Will they be for the world at large?