The only thing I understand deeply, because in my teens I was thinking about it, and every year of my life, is software. So I'll never be hands-on on anything except software.

You may have heard of Black Friday and Cyber Monday. There's another day you might want to know about: Giving Tuesday. The idea is pretty straightforward. On the Tuesday after Thanksgiving, shoppers take a break from their gift-buying and donate what they can to charity.

In 1990, one in 10 children died before the age of five. That's now down to one in 20, and vaccines were the single biggest factor in that. Had it stayed at 10 percent, 122 million more children would have died.

In business, the idea of measuring what you are doing, picking the measurements that count like customer satisfaction and performance... you thrive on that.

My fascination is broadly with biology and the fact that our increased understanding of biology allows for breakthroughs in a broad set of diseases.

For one thing, there's an essential human factor in every business endeavor. It doesn't matter if you have a perfect product, production plan and marketing pitch; you'll still need the right people to lead and implement those plans.

We should all grow our own food and do our own waste processing, we really should.