Once you embrace unpleasant news, not as a negative but as evidence of a need for change, you aren't defeated by it. You're learning from it.

The general idea of the rich helping the poor, I think, is important. That your sense of justice says, why should rich kids - who barely get these diseases and almost never die of them - why should they get the vaccines, when poor kids, who actually do die from these diseases, don't get those things? It's an unbelievable inequity that there isn't that access.

If you rely too much on the people in other countries and other companies, in a sense that's your brain and you are outsourcing your brain.

In most of these things our foundation is a co-funder, so I can say that a polio or an HIV vaccine, that I'm putting our resources behind it in a very big way and the U.S. government would be the best partner for those efforts.

The barrier to change is not too little caring; it is too much complexity. To turn caring into action, we need to see a problem, see a solution, and see the impact. But complexity blocks all three steps.

This is a fantastic time to be entering the business world, because business is going to change more in the next 10 years than it has in the last 50.

There are people who don't like capitalism, and people who don't like PCs. But there's no-one who likes the PC who doesn't like Microsoft.