I think Eddie Izzard is one of the brightest minds of our generation. I don't see him as a comedian as much as I see him as a philosopher. I hope I get to work with him on everything until I die, because I think he has a great mind and is a very talented actor.

The idea of suggesting that Hannibal Lecter - in the book, he has a sixth finger and red eyes, and so there is a devilry in Thomas Harris' presentation - so it felt like it was completely honest and appropriate for the character. And we often talk in the writers' room, "Okay, there is the Hannibal as the devil explanation of that plot point, but we also need to ground that in a reality that is answerable to the physics of the storytelling."

Everything was so designed by Hannibal to break down Will in the first season, until Will's sanity became questionable. It's so much easier to believe that somebody losing their mind is capable of terrible things than it is to consider Frasier Crane, a charming, fun doctor who invites you to dinner. If you put those two in a police lineup, you're going to pick the guy who's melting down.

A poor white woman from the South is different than a poor black woman from the South, and has a completely different experience.

We often do to people what people are very comfortable with doing to animals without a second thought.

I've never been one of those to kind of like, 'I want somebody to do something against their nature to titillate me.' That never holds any interest. And I always want people to be who they are and if they're being not who they are I feel like it's false and, therefore, less easy to connect to. I don't need them to kiss or to display physical intimacy. I think that almost becomes too obvious. I love playing in the suggestive.

I, as the writer, can be very clear that I am writing a work of heightened fiction, as opposed to documenting horrible things that happen every day in the world. Which I have no interest in doing.